Phase Two Ventures

www.phasetwo.vc

VCMatch tracks Phase Two Ventures as an investor focused on Biotech, Medtech, and AI/ML companies, Pre-Seed and Seed rounds, and San Diego, Ca and United States markets. Upload your deck to compare your startup against the full private matching profile.

Check Size

Not specified

Stages

Pre-Seed, Seed

Focus Areas

Biotech, Medtech, AI/ML

Geography

San Diego, CA and United States

Investment Thesis

Phase Two Ventures aims to “unlock[] the potential of exceptional life science technologies and entrepreneurs” by focusing on early-stage companies that build the tools and platforms enabling future discoveries. The firm emphasizes founder/operator experience and a hands-on approach — “co-founded by entrepreneurs with years of operational experience” — and seeks to translate early technology into commercial success by “providing capital, coaching, and support” to pre-seed startups.

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Investment Focus

Who should take a closer look

Phase Two Ventures is most relevant for founders raising Pre-Seed and Seed rounds in Biotech, Medtech, AI/ML, and Hardware, especially across San Diego, CA and United States.

Focus statement

"Phase Two Ventures is a seed venture fund based in San Diego investing in early-stage life science tools, platform technologies and computational biology to support the next generation of basic research, diagnostics, and therapeutics."

Value Add

Explicit tooling/platform focus: prioritizes R&D tools, platform technologies and computational biology (not broad biotech therapeutics).
Founded and run by operators: "co-founded by entrepreneurs with years of operational experience" who have founded and scaled companies (e.g., NanoCellect, Arima Genomics, Defined Bioscience).
Hands-on support at pre-seed/seed stage: offers "capital, coaching, and support" rather than passive capital.
Deep domain/advisory network: advisors and partners with senior industry pedigree (e.g., former Agilent CTO Darlene Solomon; founders of Mesa Biotech).
Track record oriented toward productizable tools and exits (portfolio notes include companies acquired by Thermo Fisher and Dexcom).
Geographic / sector positioning: San Diego-based life-science seed fund with an explicit "Tech+Bio is the Future" positioning.