OCTANe

octaneoc.org

Octane focuses on early-stage tech, medtech, and climate tech companies in Southern California, with their Boost Venture Fund concentrating on ophthalmology, cardiology, neuro, and aesthetics sectors. They aim to create 55,000+ jobs in Southern California by 2030.

Check Size

$200K - $500K

Stages

Pre Seed, Seed, Series A

Focus Areas

Healthtech, Medtech, Digital Health

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Investment Thesis

Octane operates as an ecosystem connector rather than a traditional VC firm, believing in convening people, resources, and capital to enable startup growth. Their philosophy centers on replacing trial-and-error with engineered roadmaps and expert-backed execution. They invest in traction and de-risk early-stage capital through pre-built commercialization systems, particularly in healthcare innovation where they have deep embedded networks across physicians, KOLs, and strategics.

What Sets Them Apart

Home-court advantage: They run the events and conferences where strategics show up, providing native access to acquirers and KOLs rather than seeking external networks
De-risked capital model: Every Boost deal is vetted with key acquirers upfront, not just 'hoped for' exits
Pre-built execution deliverables: Companies receive 13 pre-built execution frameworks covering IP, clinical, regulatory, and GTM strategies
Proven track record: Octane has scaled 2,000+ startups, raised $10.5B, and driven $11.1B in exits
Multi-stage support: Integrated approach from no-cost LaunchPad SBDC accelerator through Capital & Growth to Boost Venture Fund
Physician-led investment circle: 40 LPs primarily composed of physicians who mentor, advise, and guide trials