Define Ventures

www.definevc.com

VCMatch tracks Define Ventures as an investor focused on Healthtech, Digital Health, and AI/ML companies, Pre-Seed and Seed rounds, and United States and North America markets. Upload your deck to compare your startup against the full private matching profile.

Check Size

Not specified

Stages

Pre-Seed, Seed, Series A

Focus Areas

Healthtech, Digital Health, AI/ML

Geography

United States and North America

Investment Thesis

Define Ventures invests with the conviction that the next generation of healthcare will be shaped by the convergence of deep healthcare expertise and a technology-driven mindset. They focus on early-stage health tech companies and emphasize hands-on, high-conviction partnership — using operational experience, a curated advisor bench, and active go-to-market, talent, and capital support to help founders scale category-defining companies.

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Investment Focus

Who should take a closer look

Define Ventures is most relevant for founders raising Pre-Seed, Seed, and Series A rounds in Healthtech, Digital Health, AI/ML, and Enterprise SaaS, especially across United States and North America.

Focus statement

"Define Ventures is one of the largest funds focused on early-stage health tech companies." They target health tech startups that combine healthcare domain expertise with technology-first approaches to build category-defining businesses.

Value Add

Curated cross-functional team: "Our thoughtfully curated team brings together founders, investors, and operators from category-defining companies."
Combined healthcare + Silicon Valley expertise: "bringing together the best of Silicon Valley and healthcare" and "deep healthcare expertise with a technology-driven mindset."
Proven outcomes and track record: "$23 Billion in exit value" and they state they've "helped our founders raise $1.6 billion in new capital since we initially invested."
Operational, hands-on support across GTM, talent, and capital: "Pipeline & GTM... Over half of our partner companies have customers from our coalition of large health systems, health plans, employers, and life sciences companies."; "We've placed senior level talent, board members, and advisors at 2 in 3 of our partner companies."
High-conviction, offensive approach: they say they "pull the full weight of our network and expertise to play offense and generate results" and describe themselves as "a high-conviction, hands-on team."
Values-driven founder partnership: they prioritize founders who use a "principled approach to building impactful companies" and emphasize enduring, aligned partnerships that persist through hard times.